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STAT: 79-year-old given special access to Eli Lilly obesity drug

scienceJun 23, 2026294,164

STAT reports that Eli Lilly and the FDA granted compassionate-use access in April to retatrutide, the company’s experimental next-generation obesity drug, for a single 79-year-old patient. The application was arranged by a senior NIH physician and approved by the FDA to treat refractory obesity complicated by obstructive sleep apnea and pulmonary hypertension. STAT did not identify the patient, and the one-off exemption spotlights questions about equity, regulatory oversight, and safety when powerful unapproved weight-loss therapies are provided outside clinical trials.

Lizzy Lawrence
@lizzylawrence.bsky.social

EXCLUSIVE: Eli Lilly gave compassionate use access to retatrutide, their unapproved powerful obesity drug, to a 79-year-old man in April. The application was arranged by a top doctor at NIH, and cleared by the FDA. www.statnews.com/2026/06/23/e...

21044h ago
Lizzy Lawrence1170

Sources told STAT that application drew interest from top health officials. Given the demographics and the peculiar nature of the application, I asked the WH if this patient was President Trump, who turned 80 a week ago. I did not get a direct answer.

Mr. Skeets391

C’monnnnn, previously unknown side effects

Douglas Natelson284

Anyone want to bet that there will be another story about special access to unapproved Alzheimer’s treatments?

A humble marshmallow208

The words “patients with serious and immediately life-threatening medical issues” in the article gives me hope 😊

Laminariales91

Not that Trump would have to follow any rules in our stupid lawless John Roberts country, but sleep apnea is one of the conditions treated by retatruide/GLP-3, and Trump certainly seems like he has it.

Our Lady of Perpetual Disappointment61

Compassionate use when there are other effective weight-loss drugs available? What else does it do?

Gutt “EPSTEIN” Levy50

Everybody buy a lottery ticket, here’s the first time “Trump” and “compassionate” have ever appeared in the same story

Laura Kinsale48

What, can’t he afford Zepbound?

Mary Kate Killilea45

I support every experimental drug be tested by the President first.

Wesley32

Could the "serious and immediately life-threatening medical issue" (legal requirement) be, by chance, an aortic aneurysm?

Dirk Straun30

By chance are side effects bruised hands & swollen ankles?

Neelie27

He’s not entitled to privacy around his health.

𝘚𝘒𝘐𝘗 𝘐𝘕𝘛𝘙𝘖26

The White House physician confirmed in writing that Trump is 6’3” and 238 lbs which is 0.25 below the BMI of 30 for obesity. The physician’s report suggests Trump’s BMI is 29.75. Everything about this administration is either fake or criminal, or both.

Kristen Simplicio20

There is ongoing research into whether GLP1s can prevent Alzheimer’s. Just saying.

Veronica R. MSW, LICSW18

Well if he's taking it, it's not working.

POWERFUL CRAB FART🦀16

Congrats to our very special, very dying president

bewareofthephog.bsky.social15

I don’t think it’s working.

Wes Allen15

Trump talks constantly about "his friend" who is taking "the fat drug".

dadidoc1.bsky.social12

Apparently, a major side effect is that the gastrointestinal side effects disappear when nearby decorative objects are painted gold.

Mo Latno Bill Phelan12

Is it administered through the back of the hand?

casssax.bsky.social10

Is it injected in the back of the hand?🤚

lurkerbluesky.bsky.social9

Hilarious...he got Regeneron and now this drug first...but hey vaccines don't work.... What a complete joke...more corruption

Anonymous Canadian 🇨🇦8

What, it’s not just sauerkraut? They told everyone they were just eating a lot of sauerkraut.

erinsheehyhunt.bsky.social7

Hmmm..would that 79-year-old man now be an 80-year-old man??

Domenica7

Well that’s one way of testing it’s effectiveness. Which we can conclusively say is none.

klynnc.bsky.social5

It doesn't appear to be working.

PolittleCat 🐸5

"Compassionate use is “usually reserved for terminal illness,” said Ard, who has consulted with drug companies, including Lilly. ...Angela Fitch, chief medical officer of the obesity clinic knownwell, also said she’d never heard of Lilly offering its obesity drugs early via compassionate use."

Plain White Rapper5

Family member works for Lilly - the GLP-1s cannibalize fat AND muscle. But this one supposedly BUILDS MUSCLE, which will make this drug a next-level block buster. Compassionate use means FREE. It can be approved w the right signatures. Lilly is a flat org, no one has decision power except the CEO.

sassiesmom.bsky.social5

Side effects include sleeping in meetings more than usual

luigivercotti.bsky.social5

That’s…weird. Trump isn’t that obese, Retatrutide can take almost 30% of body weight. That kind of weight loss in an 80 year old ain’t great.

D Gulley 💙🇺🇸🇺🇦4

Seriously why can’t all over age of 65 or covered by Medicare be considered for compassionate use? Medicare does not cover any treatment for weight loss. ZERO! All the hype of lowering cost doesn’t help if your insurance doesn’t cover the treatment. People on fixed income can’t afford $100+\mo.

marty2025.bsky.social4

Doesn't he have congestive heart failure or some such thing? Reta has some pretty well documented cardiac effects, including increased HR and arrythmia. That'd be a high risk RX for him

Special K4

What is the president’s "serious or immediately life-threatening disease or condition,” which is the only available reason for compassionate use according to the FDA?

Newt4

Eli Lilly? Compassion? The company that applies roughly a 1000% markup on the insulin they manufacture? Compassion?

Barbara Banfield4

Trump could have easily obtained Zepbound without this “compassionate use” bs. He could afford to pay whatever it costs. But clearly he isn’t currently taking it.

Anthony Citrano3

Wow 👀 - I hope STAT has great web infra because this story is probably going to get the Drudge/Reddit “hug of death”. What a scoop. (Yes, I realize we don’t know who it was, but the totality of the circumstances does make it seem likely.)

PolittleCat 🐸3

"Drugmakers are required to publicly announce the existence of a compassionate use program. They will often do so by issuing press releases or posting descriptions on their website. "

🦊 🩵🐦‍⬛ Fox & Crow, for Bartleby Endeavors 🎥3

To the world’s biggest compassionate man, known worldwide for his compassion, goes a compassionate use exemption for a drug pending approval.

L3

Boy that name is a minefield if you try to say it fast, can't wait for Trump to start fielding questions about it.

spartychemist.bsky.social3

as someone who works in clin supply and trials these requests are common. What is not cool is trying to identify the patient even if it may be president

JudithFlanders3

OMG: look at the URL: www.statnews.com/2026/06/23/e...

LymeScience3

Don’t existing GLP-1s work pretty well already?

dougstevelass.bsky.social3

I certainly hope this has a very negative side effect for that particular user (a positive effect for the rest of us)

Suzanne🗽🕊️⚖️ 🇺🇸🇺🇦✍🏻🎵🎶⚾️🏴‍☠️🟧♊️2

"compassionate use access ... to a 79-year-old-man"

vadaga.bsky.social2

That may explain his hair yesterday

Brian Standard, PharmD2

That is a very interesting application of compassionate use… would trizepatide not have done exactly the same thing here?

Jumulo Jimbus2

If it is the Pres one wonders if this is an attempt to limit impulsive and erratic behavior.

Randy-B-lusky2

Is one of the myriad of side effects accelerating existing dementia? If so we have our confirmation because grandpa has gone 'round the bend and he ain't coming back.

moosky2

The Special Sauce Must Flow

Alfalphamale2

A paywall blocks it, But I'm guessing Trump

dianecheyanne.bsky.social2

The guy who name called Chris Christie fat is in fact fat himself.

jim0novak.bsky.social2

Once again: HIPAA should be amended to require complete and timely public disclosure of all medical information about presidents.

You have to be realistic about these things.2

I don't understand. At 6'3", 238 lbs. Trump isn't obese. Why would he need an anti-obesity drug?

Ari is logged out mentally for good2

Ok but, not everyone is a medical professional so paywalling this feels crazy?

Scotty Taylor2

Trump talking about GLP-1s in April at an EO signing for mental health. Dude’s brain is leakier than a sieve, so I’m gonna guess GLP-1s were on his mind bsky.app/profile/atru...

baja-hacker.bsky.social2

I would have figured raw milk, tanning his balls, ivermectin and swimming in raw sewage would have been enough . . .

emptywheel
@emptywheel.bsky.social

STAT News asked whether Trump is the single then-79 year old patient who got privileged access to an Eli Lilly obesity drug. No one would deny it. www.statnews.com/2026/06/23/e...

A senior clinician at the National Institutes of Health named Ranganath Muniyappa requested the drug to treat the patient for refractory obesity with obstructive sleep apnea and pulmonary hypertension, a severe version of the disease. Pulmonary hypertension is high blood pressure in the lungs, which can be life-threatening. 
STAT does not know who the patient is. But given the patient demographics and the unusual nature of the application, STAT asked the White House whether the patient was President Trump, who turned 80 a week ago, is overweight, and has expressed interest in obesity drugs.
White House spokesperson Kush Desai directed STAT’s inquiry to the Health and Human Services Department. In response to STAT’s question about whether Trump has obstructive sleep apnea and pulmonary hypertension, Desai said a White House memo detailing Trump’s most recent medical evaluation “covers this.” The memo makes no mention of obstructive sleep apnea or pulmonary hypertension.
7563h ago
mscottpaper.bsky.social78

Hmm, why would the most physically fit president ever need an obesity drug??

so-what-who-cares.bsky.social34

Do the adverse side effects include rambling nonsense, operating outside of norms, inability to walk straight lines? Just curious…

jerbrad288228

Hey heart disease, blood pressure and obstructive sleep apnea -- you have one job! C'mon!

thecosmokramer.bsky.social11

If it is Trump, I wonder if he has long COVID, which can cause pulmonary hypertension as well as cardiovascular issues.

Holli Winters8

Could be why he has 22 doctors examing him. He could have heard about it and thought it would make him look younger and live longer. It isn't working from what I've seen of him lately. Most weight loss requires a change in your diet too.

Mark G7

Be still my heart. Note to Secret Service, I said MY heart, not his.

Omney (They/Them)🌈🏳️‍⚧️6

I did notice in around april-may that it seemed like he had lost weight, you could especially see it in his face. But now he's back to " normal" so I guess the drug didn't work well enough or there were many side effects.

Soulshine076316

I can personally attest to the fact that about half the people with obstructive sleep apnea develop diabetes. Factoring in his obesity and congestive heart failure makes the A1c results reported in that most recent doctors visit as believable as he weights 215 lbs. and is 6'3".

traciew.bsky.social5

Always special, never to blame.

BonaireVolt4

Obese? I thought he was in the "best shape of any president" and he was 6' 3" and 225 lbs. Or was that kg?

Warfare_Class4

But HIPAA bla, bla. We will never know.

Dorri4

If he started in April, wouldn’t there be visible evidence?

johniwaniszek.bsky.social3

Did you happen to notice when the compassionate use was authorized? I am not a subscriber. Thanks

acabdriver3

Sources close to the president denying that he's a "fat motherfucker"

Melina3

I believe that this is what is called in the Peptide world, Reta. It is supposedly miraculous and Im sure Trump can get it. Look it up on Reddit, which is where all the interesting peptide stuff is going on. Im sure he has a stack as does RFK Jr. I can send you my notes if you want a dive.

Sarah and her cats2

But he didn’t lose any weight.

jerbrad28822

"ADHD is a highly prevalent condition in the severely obese population. Treatment of ADHD is associated with significant long-term weight loss in individuals with a lengthy history of weight loss...ADHD should be considered as a primary cause of weight loss failure in the obese."

Elliskatz2

Makes me think about the recent video of him from the Knicks game where he was scarfing down fries and pizza!

mommak.bsky.social2

Honestly, I don’t mind the president getting treatment if he needs it, even treatment others can’t get (ie, Covid treatment from Regeneron), but these are serious health issues about which the public should be told.

Wayne Gauthier🇨🇦🇰🇷2

Anything to keep Filet-O-Fish in the White House meal rotation.

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